When is statistical significance not significant?

Statistical significance: is it really that significant?

when appropriate statistical analysis is dismissed

Predictive Ability of Statistical Genomic Prediction Methods When Underlying Genetic Architecture of Trait Is Purely Additive

A simulation study was conducted to address the issue of how purely additive (simple) genetic architecture might impact on the efficacy of parametric and non-parametric genomic prediction methods. For this purpose, we simulated a trait with narrow sense heritability h2= 0.3, with only additive genetic effects for 300 loci in order to compare the predictive ability of 14 more practically used ge...

Economic-Statistical Design of a Control Chart for High Yield Processes When the Inspection is Imperfect

CCC-r control chart is a monitoring technique for high yield processes. It is based on the analysis of the number of inspected items until observing a specific number of defective items.  One of the assumptions in implementing CCC-r chart that has a significant effect on the design of the control chart is that the inspection is perfect. However, in reality, due to the multiple reasons, the...

Grapefruits and drugs: when is statistically significant clinically significant?

Editorial Lown et al. (1) report a significant advance in describing a new mechanism by which ingested nutrients may change exposure to drug therapy. Grapefruit juice was reported to increase plasma concentrations of felodipine and nifedipine when the drug was concurrently administered with grapefruit juice (2). The potential clinical importance of such an interaction was noted when cyclosporin...